Effects of synthetic cecropin analogs on in vitro growth of Acholeplasma laidlawii.
نویسندگان
چکیده
Four synthetic peptides (Peptidyl MIMs; Demeter Biotechnologies, Inc.) were evaluated for their in vitro activity against Acholeplasma laidlawii. Fifty percent effective concentration values ranged from 1 to 15 microM. Three of these compounds are more lethal than cecropin B against A. laidlawii.
منابع مشابه
Adaptation to Unfavorable Conditions of Growth: Pathogenicity of Acholeplasma Laidlawii Pg8
As a result of cultivation of A. laidlawii PG8 cells on the deficient medium during 480 days, the mycoplasma culture adapted in vitro to unfavorable growth conditions was obtained. The culture consisted of cells with sizes less than 0.2 μm and features of A. laidlawii PG8 ultramicroforms, nanocells. A. laidlawii PG8 culture adapted in vitro to unfavorable growth conditions shows more evident ph...
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An Acholeplasma laidlawii variant has been isolated that has a REP- phenotype. The properties of this variant, relative to parental cells, are: (i) it exhibits no change in cell growth kinetics; (ii) it does not propagate single-stranded deoxyribonucleic acid (DNA) mycoplasmaviruses but does propagate double-stranded DNA mycoplasmaviruses; (iii) it converts parental circular single-stranded myc...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 45 6 شماره
صفحات -
تاریخ انتشار 2001